The Food and Drug Administration (FDA) has only approved the use of artificial disc replacement (ADR) for one-level lumbar disc replacement. Two-level ADR are undergoing studies now.
It will be quite some time before long-term results are really known for this new treatment. Scientists say there are many variables to be studied and defined. How long do the implant components last? What’s the effect on the segments above and below? In particular, what happens at the joints, discs, and soft tissues above and below the ADR? Does load increase or decrease? Does the motion increase, decrease, or stay the same?
Right now computer simulations are being used to test results using one- versus two-level ADRs. Various studies are also looking at what happens when a patient has a spinal fusion at one level and goes back later for an ADR at the next level. How does this compare to someone who had two ADRs and no fusion?
With new technology and improved implant designs, these (and many other) questions will be answered in time. For now your orthopedic surgeon can advise you as to what is best for your situation.