Studies have shown that taking creatine supplements can help patients regain strength after surgery. However, a recent study of patients after total knee replacement didn't reproduce these findings. In fact, knee and ankle strength went down 30 days after the operation.

This study may be the first to point out the importance of physical activity and exercise when taking creatine. Movement and especially resistance to muscles seem to help the creatine get ransported into the muscles for active use.

Taking creatine supplements before and after joint replacement isn't advised at this time. Talk to your doctor before taking any supplements. Some supplements shouldn't be taken with other drugs or combined with anesthesia.