Research has shown that you can set up your split keyboard in a variety of ways and still maintain the healthy wrist position that can ease wrist strain. You could, for example, separate the two halves so your hands are shoulder-distance apart. Angling the two halves outward slightly can help keep your wrists in a straight line. Either way, you may have fewer problems when the keyboard sections are positioned to keep your wrists in a straight line with your forearms. You may want to work with a physical therapist to find the keyboard setup that is best for you.